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Table 1 Demographic and epidemiologic characteristics of patients

From: Comprehensive analysis of chronic hepatitis B concurrent with non-alcoholic fatty liver disease: a proteomics report based on clinical liver samples

Variables (n [%] or median [IQR])

HC (n = 6)

CHB(n = 8)

NAFLD(n = 7)

CHB + NAFLD(n = 10)

p value

Age (ys)

35

39.00(31.25–42.25)

36.00(28.00–43.00)

35.50(33.25–39.25)

 

Sex

     

 Female (%)

2 (33.3)

6 (75)

5 (71.4)

1 (10)

 

 Male(%)

4 (66.7)

2 (25)

2 (28.6)

9 (90)

 

 BMI

22.32(19.96–25.36)

21.88(19.82–24.36)

42.72(35.50-44.22)

25.86(23.20-27.52)

*1

Blood routine

     

AST(U/L)

20.68(16.34–26.12

19.55(14.28–24.80)

38.80(16.90–64.00)

31.30(23.1-40.28)

*1

ALT(U/L)

16.40(14.80-30.54)

17.40(14.40-34.13)

48.55(39.78–62.98)

61.90(37.00-76.70)

*1

TG(mmol/L)

0.89(0.69–1.13)

0.77(0.66–0.90)

1.92(1.44–2.60)

1.91(1.35–3.04)

**1

TC(mmol/L)

4.19(3.19–5.12)

4.39(3.89–5.15)

5.81(4.48–6.15)

4.88(3.96–5.01)

*1

HDL (mmol/L)

1.78(1.17–1.61)

1.56(1.27–1.78)

1.04(0.99–1.06)

0.87(0.72–1.09)

 

LDL(mmol/L)

2.49(2.05–2.68)

2.49(2.05–2.68)

4.03(2.47–4.51)

3.15(2.25–3.29)

 

GGT(U/L)

15.78(12.44–27.85)

13.65(11.43–18.65)

61.60(38.70-104.10)

49.60(27.98–72.55)

*1

UA (µmol/L)

310.50(230.00-359.00)

270.50(227.00-330.00)

439.00(401.00-533.00)

435.00(383.00-510.25)

*1

ALP(U/L)

45.35(41.24-68.215)

48.35(40.25-63.975)

84.90(59.60-105.10)

63.90(53.40-86.78)

 

ALB (g/L)

42.97(40.33–44.46)

43.05(40.28–47.08)

44.00(40.90–45.50)

43.60(41.58–45.23)

 

FBG (mmol/L)

4.05(3.43–4.74)

4.27(3.83–4.45)

6.13(5.49–7.61)

4.33(4.15–4.63)

*2

TB (µmol/L)

8.90(6.50–11.30)

14.90(7.50-15.88)

12.95(9.50–15.30)

8.70(5.80–10.70)

 

HBsAg(log10IU/mL)

 

3.86(2.93–4.48)

0

3.68(2.29–4.25)

 

HBeAg positive(%)

 

5(62.5)

0

8(80)

 

HBV-DNA(log10IU/mL)

 

3.90(3.32–7.93)

0

3.26(2.86–5.06)

 
  1. Notes 1:CHB and CHB + NAFLD; 2:NAFLD and CHB + NAFLD.*, p < 0.05; **, p < 0.001
  2. Abbreviations ALT, alanine transferase; AST, aspartate transferase; TG, triglyceride; TC, total cholesterol; HDL, high density lipoprotein; LDL, low density lipoprotein; ALP, alkaline phosphatase; GGT, γ-Glutamyl transferase; TB, total bilirubin; ALB, albumin; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B s antigen; UA, uric acid; FBG, asting blood glucose