Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF)

Table 2 A semi-quantitative analysis of liquid biopsies for breast cancer biomarker scanning

Liquid biopsy	Volume	Accessibility	Discomfort	Reference sample	Sample preparation	Biomarker concentration	Patient-led collection	Convention
Plasma	++	+++	+++	Absent	++++	++	Absent	+++++
Urine	+++++	+++++	+	Absent	+++	+	Present	++++
Saliva	+++	+++++	+	Absent	++	+	Present	+++
Ductal lavage	+	+	++++	Present	+	+++++	Absent	+
Random Periareolar Fine Needle Aspiration	+	+	+++++	Present	++	+++++	Absent	+
Nipple Aspirate Fluid	+	+++	++	Present	+	+++++	Present	++

ISSN: 1559-0275